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| Ridsbaide | Дата: Суббота, 22.03.2014, 09:53 | Сообщение # 1711 |
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| Ridsbaide | Дата: Воскресенье, 23.03.2014, 08:54 | Сообщение # 1712 |
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| Ridsbaide | Дата: Вторник, 25.03.2014, 01:52 | Сообщение # 1713 |
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| ninakmox | Дата: Пятница, 04.04.2014, 06:57 | Сообщение # 1714 |
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| BKzCQ | Дата: Суббота, 05.04.2014, 15:34 | Сообщение # 1715 |
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| ShgCR | Дата: Воскресенье, 06.04.2014, 01:31 | Сообщение # 1716 |
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| GEXrJ | Дата: Воскресенье, 06.04.2014, 07:51 | Сообщение # 1717 |
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| ymLxD | Дата: Воскресенье, 06.04.2014, 09:30 | Сообщение # 1718 |
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| HTflk | Дата: Воскресенье, 06.04.2014, 10:49 | Сообщение # 1719 |
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| TLtpC | Дата: Воскресенье, 06.04.2014, 12:23 | Сообщение # 1720 |
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| cQIlr | Дата: Понедельник, 07.04.2014, 03:24 | Сообщение # 1721 |
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| orqwrqnsgxl | Дата: Среда, 09.04.2014, 23:06 | Сообщение # 1722 |
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| coueapwx | Дата: Суббота, 12.04.2014, 22:47 | Сообщение # 1723 |
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| jxqovjmsagj | Дата: Понедельник, 14.04.2014, 14:02 | Сообщение # 1724 |
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Группа: Бомж
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| fmyykjz | Дата: Четверг, 17.04.2014, 06:26 | Сообщение # 1725 |
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Группа: Бомж
| Daptomycin is a cyclic lipopeptide antibiotic produced by the organism Streptomyces roseosporus.<>4 - <>5 - Daptomycin consists of thirteen amino acids, ten of which are arranged in a cyclic fashion, and three that adorn an exocyclic tail. Two non-proteinogenic amino acids exist in the lipopeptide, the unusual amino acid L-kynurenine (Kyn), only known to Daptomycin, and L-3-methylglutamic acid (mGlu). The N-terminus of the exocyclic tryptophan residue is coupled to decanoic acid, a medium chain (C10) fatty acid. Biosynthesis is initiated by the coupling of decanoic acid to the N-terminal tryptophan, followed by the coupling of the remaining amino acids by nonribosomal peptide synthetase (NRPS) mechanisms. Finally, a cyclization event occurs, which is catalyzed by a thioesterase enzyme, and subsequent release of the lipopeptide is granted.
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